FOXO4-DRI CAS:2460055-10-9
Product Detail
Name: FOXO4-DRI CAS:2460055-10-9
Feature:
FOXO4-DRI is a cell-permeable peptide comprising part of the p53-interaction domain of FOXO4. It can compete with endogenous FOXO4 for p53, thereby disrupting the FOXO4-p53 interaction. Disrupting the p53-FOXO4 interaction causes p53 to be excluded from the nucleus and directed to mitochondria for induction of apoptosis in senescent cells, ultimately eliminating senescent fibroblasts through triggering apoptosis[1-2]. FOXO4-DRI to be selective for ionizing radiation-induced senescent IMR90 cells and safe to normal cells.
Composition:
Appearance: White powder
Assay: 99%
Packing: 25kg/drum or as discussed
Shelf Life: 2 years
Storage: Store in cool and dry area
Certification:ISO GMP KOSHER HALAL