3-Indolepropionic Acid, also known as indolepropionic acid; Azaindenyl propionic acid; Indolyl-3-propionic acid, white flake crystal. Gradually change color in exposed air. It is easily soluble in ethanol, ether, acetone, benzene, chloroform and ethyl acetate, soluble in hot water and difficult to dissolve in cold water. It is mainly used as pharmaceutical intermediates and plant growth stimulants.
Aniline hydrochloride was diazotized with sodium nitrite under acidic conditions, and then reacted with ethyl cyclopentanone-2-carboxylate α- Phenyl hydrazone carbonyl oxalate. The obtained phenylhydrazone was dissolved in ethanol solution containing 20% sulfuric acid and refluxed for 4H to produce indole-2-carboxylic acid-3-propionic acid. Heat it to 225-230 ℃ for about half an hour. At the end of the reaction, dissolve the reactant in boiling water, add activated carbon to decolorize and filter. The filtrate was concentrated, crystallized and recrystallized with hot water to obtain 3-indolepropionic acid. The natural compound indole-3-propionic acid (IPA) is an important intermediate for the synthesis of indole alkaloid ergic acid.
Characteristics of indolepropionic acid
White or light brown acicular crystal, melting point 134 ℃. Slightly soluble in water. Soluble in ethanol, acetone, chloroform, dimethylformamide and benzene. It is stable in acidic solution and decomposes under ultraviolet light. Indolepropionate is soluble in water.
Effect of indolepropionic acid
Indolepropionic acid can be absorbed by roots, stems, leaves and flowers. It can promote the formation of roots and prolong the residence time of fruits on plants. It can promote rooting, fruit setting and other physiological functions. Indolepropionic acid is not oxidized in plants. Therefore, indolepropionic acid is relatively stable.
Use of indolepropionic acid
At the same dose, the ability of indolepropionic acid to promote crop root formation is lower than indole butyric acid, so indolepropionic acid is rarely used in crops. The main function of indolepropionic acid is to promote the formation of asexual flowers of persimmon and eggplant at the dose of 100 ~ 500 mg / L.
Post time: Dec-20-2021