Ferulic acid was first found in plant seeds and leaves. It is a phenolic acid widely existing in plants. It combines with polysaccharides and proteins to form the skeleton of cell wall in cell wall, and rarely exists in free form. It has high content in ferula, Cimicifuga, Angelica sinensis, wild jujube kernel and other traditional Chinese medicine. It is one of the effective components of these traditional Chinese medicine. Ferulic acid exists in edible plants such as onion and chrysanthemum, and the ferulic acid content of food raw materials such as chaff, coffee, wheat bran, rice bran, bagasse and beet meal is also high. Ferulic acid has good pharmacological action and biological activity, so it has high application value in medicine, health products and cosmetic raw materials.
Ferulic acid can resist bacteria and inflammation. It was found that ferulic acid had a certain inhibitory effect on Escherichia coli, Bacillus subtilis, Staphylococcus aureus and yeast, but had a poor effect on mold. Bai Changli et al. Found that the important monomer ferulic acid can inhibit the replication of PrPSc protein in Scn2a by Western blot, and speculated that the traditional Chinese medicine monomer ferulic acid may play a certain therapeutic role in prion diseases.
Ferulic acid can fight cancer. As early as 2002, Japan’s Wakayama Industrial Technology Center extracted ferulic acid from rice bran and chemically combined the aromatic alcohols in the remaining citric acid grass oil to make the anti-cancer substance egmp. According to animal experiments, egmp has the effect of preventing colorectal cancer, and it is very safe and convenient to use. In recent years, there are many studies on ferulic acid against colon cancer. Kawabata et al. M1 used azomethane (AOM) to induce the formation of colon cancer in f334 mice. It was found that the number of abnormal focus crypts fed with 500mg / kg ferulic acid decreased by 27%.
Ferulic acid also has the effects of preventing blood lipid oxidation, anti platelet aggregation and thrombosis, improving cardiovascular and cerebrovascular health, preventing bone loss, improving women’s climacteric syndrome, and restoring and improving memory for the elderly.
Post time: Aug-02-2021