Florfenicol is a veterinary antibiotic commonly used at present, with a wide antibacterial spectrum, strong bacteriostatic effect, low minimum inhibitory concentration (MIC), antibacterial effect is 15-20 times that of chloramphenicol, thiamphenicol, after feed administration In 60 minutes, the drug concentration in the tissue can reach the peak, which can quickly control the condition, high safety, non-toxic, no residue and other characteristics, no hidden danger of aplastic anemia, suitable for large-scale large-scale farms, mainly used for treatment Bovine respiratory diseases caused by Pasteurella and Haemophilus. It has good curative effect on bovine hoof disease caused by Fusobacterium. It is also used for swine and chicken infectious diseases and fish bacterial diseases caused by sensitive bacteria. Florfenicol is not easy to produce resistance: because the fluorine atom is used to replace the hydroxyl group in the molecular structure of thiamphenicol, it effectively solves the problem of resistance to chloramphenicol and thiamphenicol. Strains resistant to thiamphenicol, chloramphenicol, amoxicillin, and quinolones are still sensitive to this product. Because chloramphenicol has serious adverse reactions such as aplastic anemia and immunosuppression, it is prohibited to be used in the production of food animals. The characteristics of florfenicol are: broad antibacterial spectrum, against Salmonella, Escherichia coli, Proteus, Haemophilus, Actinobacillus pleuropneumoniae, Mycoplasma hyopneumoniae, Streptococcus suis, Pasteurella suis, Bordetella septicum , Staphylococcus aureus, etc. are sensitive. The drug is easy to absorb and widely distributed in the body. It is a fast-acting, long-acting preparation, without the hidden danger of aplastic anemia, and has good safety. In addition, the price is moderate, and it is cheaper than other drugs for preventing and treating respiratory diseases such as tiamulin (mycoplasma), tilmicosin, azithromycin, etc., and the cost of medication is easy for users to accept. Because of these characteristics, domestic florfenicol has been widely used, becoming the current drug of choice for the prevention and treatment of bacterial infections in the respiratory and digestive tracts of livestock and poultry. Florfenicol should not be used in combination with quinolones, penicillins, cephalosporins, or with ampicillin, sulfonamides, or furans.
Florfenicol can strongly interfere with bacterial protein synthesis, rapid absorption, wide distribution in the body, long half-life, no aplastic anemia side effects, easy to produce drug resistance, no residue, no cross drug resistance. Florfenicol can be used for the treatment of systemic infections in livestock and poultry and aquatic animals, and has a significant effect on respiratory infections and intestinal infections.
Poultry: mixed infection caused by various sensitive bacteria such as colibacillosis, salmonellosis, infectious rhinitis, chronic respiratory disease, duck plague.
Livestock: pigs, cattle, sheep and other infectious pleurisy, asthma, streptococcus disease, Escherichia coli disease, salmonellosis, infectious pleura pneumonia, asthma, paratyphoid of piglets, yellow and white dysentery, edema disease, atrophic rhinitis, pig lung Epidemic, red and white dysentery of piglets, and milk-free syndrome.
Crabs: appendage ulcer disease, yellow gills, rotten gills, red legs, glow inflammation and red body syndrome, etc.
Soft-shelled turtle: Red neck disease, furuncle disease, perforation disease, rot skin disease, enteritis, mumps bacterial sepsis, etc.
Frogs: Cataract syndrome, ascites disease, sepsis, enteritis, etc.
Fish: Enteritis, ascites, vibriosis, Edwardsiosis, etc.
Eel: desticky sepsis (unique effect), Edwardsiosis, erythroderma, enteritis, etc.
Post time: Jun-23-2020