Glucosamine Sulfate is a natural derivative of aminomonosaccharide, which is an important component in the synthesis of proteoglycan in cartilage matrix. Proteoglycan can make articular cartilage absorb impact force by inhibiting the tensile force of collagen fibers. In the early stage of joint degenerative disease, the biosynthesis of agglomerated glucosamine is increased; In the later stage of the disease, the opposite is true. As a result, the elasticity of cartilage is weakening and many symptoms of arthritis appear gradually. Aminomonosaccharide can stimulate chondrocytes to produce glycoprotein with normal polymer structure, inhibit some enzymes (such as collagenase) that can damage articular cartilage, prevent the damage of chondrocytes caused by corticosteroids and some non steroidal anti-inflammatory drugs, and reduce the release of endotoxin factors in injured cells.
Glucosamine sulfate can help the human body relieve fatigue. People who often exercise and travel around often suffer from soreness of waist and knee if they don’t pay attention to maintenance. This kind of symptom will make the human body feel irresistible fatigue. Glucosamine sulfate can help relieve joint pressure and back pain, so as to relieve fatigue.
Reginster et al. Studied the long-term effect of glucosamine sulfate on osteoarthritis. 212 patients with knee osteoarthritis were randomly divided into two groups, taking 1500 mg glucosamine sulfate or placebo every day for 3 years. Before treatment and 1 year and 3 years after treatment, the anteroposterior X-ray pictures of each knee were taken when it was fully extended and loaded. The average width of the middle space of tibia and femur joints was measured by digital image analysis. The minimum joint cavity width is the narrowest part of the joint cavity. The results show that it is developing in a better direction when observed with a magnifying glass. Therefore, it is considered that the long-term treatment of glucosamine sulfate can prevent the development of knee OA and improve the joint structure.
Glucosamine sulfate can resist arthritis. Studies have shown that glucosamine has antioxidant effect and inhibits the production of superoxide free radicals in injured cells. Through the above ways, glucosamine can play a direct anti-inflammatory role, relieve the pain symptoms of osteoarthritis, improve joint function, and prevent the development of osteoarthritis.
Post time: Jul-28-2021