Sulfamonomethoxine, or sulfa-6-methoxypyrimidine, has a strong antibacterial effect and also has a significant effect on coccidia and toxoplasma. Oral administration is easy to absorb, the acetylation rate is low, and it is not easy to produce crystal urine and hematuria. It is used to treat various sensitive bacterial infections, avian coccidiosis, and swine toxoplasmosis. It has the strongest effect on Streptococcus, Pneumococcus, Salmonella, Pasteurella, Corynebacterium pyogenes, Escherichia coli, and also has antibacterial effect on Staphylococcus, Proteus, Bacillus anthracis, etc., so it is widely used in livestock and poultry respiratory tract, gastrointestinal tract Tract, urinary tract infections. However, it is more commonly used for the emergency treatment of outbreaks of leukocyte protozoosis and coccidiosis in poultry. It is also highly effective for toxoplasmosis of pigs. This product is a newer long-acting sulfonamide. Its antibacterial spectrum is similar to sulfadiazine, but its antibacterial effect and protection against animal infections are stronger than other sulfonamides.
This product is a long-acting sulfonamide drug, which is suitable for non-enzymatic Staphylococcus aureus, Streptococcus pyogenes, Streptococcus pneumoniae, Escherichia coli, Klebsiella, Salmonella, Shigella and other Enterobacteriaceae Bacteria, Neisseria gonorrhoeae, Neisseria meningitidis, Haemophilus influenzae have antibacterial effect. Sulfa drugs are broad-spectrum bacteriostatic agents. Its mechanism of action is similar to that of p-aminobenzoic acid (PABA) in structure, and can compete with PABA to the dihydrofolate synthase in bacteria, thereby preventing PABA from being used as a raw material to synthesize the folic acid required by bacteria, reducing metabolic activity. The amount of hydrofolate, which is essential for bacteria to synthesize purines, thymine nucleotides, and deoxyribonucleic acid (DNA), thus inhibiting the growth and reproduction of bacteria.
Sulfamethoxine as a broad-spectrum antibacterial agent is effective against hemolytic streptococcus, pneumococcus, and E. coli. Mainly used for the treatment of urinary tract infections and respiratory tract infections, it also has a killing effect on animal mycoplasma, Ixoplasma and coccidiosis.
Post time: Jun-11-2020