Testosterone propionate is a synthetic androgen, and its mechanism of action is not fully understood. It can inhibit the secretion of FSH from the anterior pituitary, reduce the secretion of estrogen by the ovary, and counter the effects of estrogen. Experiments have found that the occurrence of breast cancer in mice is closely related to ovarian function. Injecting estrogen can increase the incidence of breast cancer in female mice and make male mice also develop breast cancer; the application of high doses of this drug can reduce high breast cancer The incidence of breast cancer in mice. It has obvious protein assimilation and promotes protein synthesis. In addition, it can improve the general condition of patients with advanced tumors, and can promote the production of red blood cells and the synthesis of hemoglobin to improve anemia.
Testosterone propionate is an androgen and anabolic hormone. It can promote the formation, fertility and maturity of male sexual organs, resist estrogen, inhibit endometrial growth and ovarian pituitary function. Promote protein synthesis and metabolism, excite bone marrow hematopoietic function, and stimulate the production of blood cells. Although this product can be absorbed orally, it is destroyed in the liver and becomes invalid. Therefore, intramuscular injection is generally used. After intramuscular injection, the absorption is slower, and the delay time is 2 to 4 days. The plasma protein binding rate is 98%, and the half-life is 10-20 minutes.
The main role of testosterone propionate is to promote the formation of male sexual organs and the development and maintenance of secondary sexual characteristics. In addition, it has protein assimilation, promotes the fusion of long bone epiphyses, and stimulates the proliferation of red blood cells. Clinically, it is mainly used for the replacement therapy of testicular and pituitary hypofunction; using the opposite effect of estrogen to treat functional uterine bleeding. Because this product inhibits the secretion of gonadotropin in the anterior pituitary gland, it is used for women’s menopausal syndrome and advanced breast cancer; for aplastic anemia and other anemia.
Post time: Oct-13-2020