Orlistat
Name: Orlistat
Feature:
Orlistat, commonly used dosage forms are tablets and capsules. For anti-obesity drugs. It is used to reduce the incidence of obesity-related risk factors and other obesity-related diseases, including hypercholesterolemia, diabetes, impaired glucose tolerance, hyperinsulinemia, hypertension, and reduce the fat content in the organs . For the treatment of obese or overweight patients. Orlistat is a long-acting and potent specific gastrointestinal lipase inhibitor. It acts by forming a covalent bond with the active serine sites of gastric lipase and pancreatic lipase in the stomach and small intestine to inactivate the enzyme. Therapeutic effect. Inactivated enzymes cannot hydrolyze fats (mainly triglycerides) in food into absorbable free fatty acids and monoacylglycerols. Undigested triglycerides cannot be absorbed by the body, thereby reducing calorie intake and controlling weight.
Orlistat has application / function as follows:
1. Orlistat has the effect of weight loss, it is not an obesity treatment drug that acts on the central nervous system. It only acts on the gastrointestinal tract. By inhibiting the lipase in the gastrointestinal tract, it prevents the hydrolysis of triacylglycerols into free fatty acids and monoacylglycerides, reduces the absorption of dietary fat by the intestinal mucosa, and promotes the elimination of fat from the body. Lipase is an enzyme necessary for the digestion of fat in the gastrointestinal tract. This product can bind to the serine residues of gastric and pancreatic lipase to inactivate the lipase, so that it cannot decompose the fat in the food into free fatty acids and inhibit the fat Utilize and absorb.
2. Orlistat can maintain the body, and when used with a low-calorie diet, it can help reduce weight and maintain weight after losing weight. Orlistat is a class of drugs called lipase inhibitors. It works in your intestines and stomach and prevents certain fats you eat from being absorbed and digested. Then, these undigested fats are removed by bowel movements. It has a strong selective inhibitory effect on gastric lipase and pancreatic lipase, and has no effect on other digestive enzymes. It does not affect the intake of carbohydrates, the absorption of protein and phospholipids. The drug is not absorbed by the gastrointestinal tract, and has no effect on lipase. The inhibitory effect is reversible.
Composition:
Appearance: White powder
Assay: ≥99%
Packing: 25kg/drum
Shelf Life: 2 years
Storage: Store in cool and dry area
Certification:ISO GMP KOSHER HALAL
