Phenylephrine Hydrochloride

Name: Phenylephrine Hydrochloride

CAS: 61-76-7

Feature:

Phenylephrine Hydrochloride is a phenylephrine (PE) and an α1-adrenoceptor agonist that promotes hypertrophic growth in the ventricular myocytes, and activates several MAPK signaling pathways. Phenylephrine Hydrochloride is an activator of α1A-AR, α1D-AR and α1B-AR. Phenylephrine Hydrochloride is an adrenergic agent, which functions as a β-receptor sympathomimetic drug. Phenylephrine Hydrochloride is the pharmaceutical secondary standard for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Phenylephrine Hydrochloride is classified under the category of sympathomimetic drugs. It is generally utilized as a nasal decongestant, a mydriatic and and cardiotonic agent.

Phenylephrine Hydrochloride is the hydrochloride salt form of phenylephrine, a direct-acting sympathomimetic amine chemically related to adrenaline and ephedrine with potent vasoconstrictor property. Phenylephrine is a post-synaptic alpha-adrenergic receptor agonist that causes vasoconstriction, increases systolic/diastolic pressures, reflex bradycardia, and stroke output.

Phenylephrine Hydrochloride has the following applications/functions:

1. Phenylephrine Hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography and spectrophotometry techniques.

2. Phenylephrine Hydrochloride can be used in the preparation and culturing of cardiocytes and fibroblasts.

3. Phenylephrine Hydrochloride can also stimulate myocardial strips to measure slice contraction.

4. It studies the effect of Kruppel-like factor (KLF) on cardiac hypertrophy in vivo in primary cardiomyocyte cultures.

5. It also evaluate the pharmacological response of embryonic stem cell (ESC)-derived cardiomyocytes.

6. Phenylephrine Hydrochloride pharmacologically rescue GATA (erythroid transcription factor) binding protein 3 (GATA3) null embryo from early embryonic lethality.

7. It can also be used for prolonging the local time in surgical operations, anti-inflammatory for nasal mucosal congestion, pupil dilation in ophthalmology, boosting of acute hypotension, and medicine for colds.

Composition: 

Appearance: White crystalline powder

Packing: 25kg/drum or as discussed

Shelf Life: 2 years

Storage: Store in cool and dry area

Certification:ISO GMP KOSHER HALAL