Trifluoroacetyl tripeptide -2 CAS:64577-63-5

Product Detail

Name: Trifluoroacetyl tripeptide -2

CAS: 64577-63-5

Feature:

A peptide is a chain of amino acids connected by peptide bonds. Peptides are mainly involved in protein regulation, angiogenesis, cell proliferation, melanogenesis, cell migration and inflammation. In the past few decades, bioactive peptides have been widely used in the cosmetic industry. Peptides need to have low molecular weight (<500 Da), high stability and solubility to reduce the diffusion of peptides between epidermal layers. Over the years, the scientific community has developed small, stable synthetic peptide fragments that can activate collagen production and reduce facial wrinkles and pigmentation. Trifluoroacetyl tripeptide-2 is a synthetic tripeptide designed as a matrix metalloproteinase and elastase inhibitor. In vitro studies were conducted to evaluate the effects of trifluoroacetyl tripeptide-2 on ECM protection, proteoglycan synthesis in cell-matrix interactions, and progerin synthesis in mature human normal fibroblasts. This protein has recently been identified As a common inducer of cellular senescence. The results show that trifluoroacetyl tripeptide-2 has a wider range of anti-aging properties. It can reduce the synthesis of presenilin, increase the production of proteoglycans and shrink collagen, so it can reduce wrinkles and increase tissue stiffness. In addition, its anti-wrinkle, anti-sagging and skin firming effects were evaluated in two in vitro split face studies. According to research, trifluoroacetyl tripeptide 2 has a gradual effect on wrinkles, firmness, elasticity and sagging.

Trifluoroacetyl tripeptide -2 has the following applications/functions:

Inhibit progeria protein synthesis and promote the production of multi-ligand proteoglycans

1.Trifluoroacetyl tripeptide-2 is an active tripeptide derived from elastase inhibitor. It can reduce the synthesis of premature aging protein and improve skin sagging, sagging and wrinkles caused by it. Studies have shown that cellular senescence is closely related to progeria proteins. As we age, premature aging proteins accumulate in the body, leading to nuclear defects and DNA damage, resulting in a series of skin aging phenomena. Trifluoroacetyl tri-2 is an active tripeptide derived from elastase inhibitor. It can reduce the synthesis of premature aging protein and improve skin sagging, sagging and wrinkles caused by it.

2.Trifluoroacetyl tripeptide-2 promotes the production of syndecan, prolongs cell lifespan, inhibits the activity of matrix metalloproteinases MMP1, MMP3 and MMP9, reduces the decomposition of extracellular matrix proteins, and maintains its integrity , Inhibit elastase activity, reduce elastin degradation, and promote skin firmer and elasticity. Proteoglycan is one of the main components of the cell matrix, and it is also the basic material required by the dermis of the skin. It has excellent moisturizing ability, can promote cell growth and accelerate skin metabolism. At the same time, it has also been proven to be effective in improving wrinkles, skin elasticity, inhibiting melanin production and pigmentation. The moisturizing effect of proteoglycan is basically the same as that of collagen and hyaluronic acid.

Composition:

Appearance:

White powder, Assay: 99%

Transparent liquid, Assay: 1000PPM

Packing: 25kg/drum or as discussed

Shelf Life: 2 years

Storage: Store in cool and dry area

Certification:ISO GMP KOSHER HALAL